Dr. David Sinclair, Professor in Genetics, Harvard Medical School 00:00:00
The Sinclair lab was the first to identify a role for NAD+ biosynthesis in regulation of lifespan, that sirtuins activated by CR in mammals (A Unified Theory of Caloric Restriction, 2005), the identification of small molecules that activate SIRT1 such as resveratrol, how organisms appear to have evolved to sense plant stress and declining food supply by having plant stress metabolites
